Water → Tert-butyl 3-[[3-[5-(azetidine-1-carbonyl)pyrazin-2-yl]oxy-5-[1-(difluoromethoxy)propan-2-yloxy]benzoyl]amino]pyrazole-1-carboxylate

HRID 938463Notes

Reaction equation

[CH3:62][CH2:63][O:64][C:65](=[O:66])[CH3:67].[Cl:1][C:2]([N:3]([CH3:4])[CH3:5])=[C:6]([CH3:7])[CH3:8].[Cl:58][CH2:59][Cl:60].[N:9]1([C:13](=[O:14])[c:15]2[n:16][cH:17][c:18]([O:21][c:22]3[cH:23][c:24]([C:25](=[O:26])[OH:27])[cH:28][c:29]([O:31][CH:32]([CH2:33][O:34][CH:35]([F:36])[F:37])[CH3:38])[cH:30]3)[n:19][cH:20]2)[CH2:10][CH2:11][CH2:12]1.[NH2:39][c:40]1[n:41][n:42]([C:45](=[O:46])[O:47][C:48]([CH3:49])([CH3:50])[CH3:51])[cH:43][cH:44]1.[OH2:61].[cH:52]1[cH:53][cH:54][n:55][cH:56][cH:57]1>>[N:9]1([C:13](=[O:14])[c:15]2[n:16][cH:17][c:18]([O:21][c:22]3[cH:23][c:24]([C:25](=[O:26])[NH:39][c:40]4[n:41][n:42]([C:45](=[O:46])[O:47][C:48]([CH3:49])([CH3:50])[CH3:51])[cH:43][cH:44]4)[cH:28][c:29]([O:31][CH:32]([CH2:33][O:34][CH:35]([F:36])[F:37])[CH3:38])[cH:30]3)[n:19][cH:20]2)[CH2:10][CH2:11][CH2:12]1