Carbon tetrabromide → 3-[3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimethoxy-benzyl)-pyrrolidin-3-yl]-propyl-bromide
Reaction equation
[C:31]([Br:32])([Br:33])([Br:34])[Br:35].[Cl:1][c:2]1[cH:3][c:4]([C:9]2([CH2:27][CH2:28][CH2:29][OH:30])[CH2:10][CH2:11][N:12]([CH2:14][c:15]3[cH:16][c:17]([O:25][CH3:26])[c:18]([O:23][CH3:24])[c:19]([O:21][CH3:22])[cH:20]3)[CH2:13]2)[cH:5][cH:6][c:7]1[Cl:8].[c:36]1([P:37]([c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[cH:50][cH:51][cH:52][cH:53][cH:54]1>>[Cl:1][c:2]1[cH:3][c:4]([C:9]2([CH2:27][CH2:28][CH2:29][Br:32])[CH2:10][CH2:11][N:12]([CH2:14][c:15]3[cH:16][c:17]([O:25][CH3:26])[c:18]([O:23][CH3:24])[c:19]([O:21][CH3:22])[cH:20]3)[CH2:13]2)[cH:5][cH:6][c:7]1[Cl:8]Participants
4
Sources & evidence
- ORD record
- ord-aef68124f31543d4b6702c13bcaed74f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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