Acetic Acid → 6-Amino-3,3-bis-trifluoromethyl-1,3-dihydro-indol-2-one
Reaction equation
[C:21]([OH:22])(=[O:23])[CH3:24].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[N:8]([OH:11])[C:7](=[O:12])[C:6]2([C:13]([F:14])([F:15])[F:16])[C:17]([F:18])([F:19])[F:20].[Zn:30]>>[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:12])[C:6]2([C:13]([F:14])([F:15])[F:16])[C:17]([F:18])([F:19])[F:20]Participants
5
Sources & evidence
- ORD record
- ord-98d309d0d5d241d5a4ab92bd9e200e24
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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