HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 938740Generated: November 1, 2026
Hydrochloric Acid → Methyl 5-(4-(1,1-difluoroethyl)phenyl)nicotinate
https://huagongshe.com/reaction/938740
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Potassium Cation | HCID 813 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Carbonate Ion | HCID 19660 | — |
| Reactant | Fluoride Ion | HCID 28179 | — |
| Reactant | (5-(Methoxycarbonyl)pyridin-3-yl)boronic acid | HCID 22309460 | — |
| Reactant | 1-Bromo-4-(1,1-difluoroethyl)benzene | HCID 45158847 | — |
| Reactant | HCID 178420554 | HCID 178420554 | — |
| Product | Methyl 5-(4-(1,1-difluoroethyl)phenyl)nicotinate | HCID 58116582 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Validation data from https://doi.org/10.1039/C8SC04228D |
|---|
| ORD ID | ord-25f40d8660af4fd9903e946d2549998c |
|---|
| Source note | Validation data from https://doi.org/10.1039/C8SC04228D |
|---|
