1-Ethylpiperazine → N-{4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-2,2,2-trifluoroacetamide
Reaction equation
[Br:1][CH2:2][c:3]1[c:4]([C:16]([F:17])([F:18])[F:19])[cH:5][c:6]([NH:9][C:10]([C:11]([F:12])([F:13])[F:14])=[O:15])[cH:7][cH:8]1.[CH2:20]([CH3:21])[N:22]1[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]1>>[CH2:2]([c:3]1[c:4]([C:16]([F:17])([F:18])[F:19])[cH:5][c:6]([NH:9][C:10]([C:11]([F:12])([F:13])[F:14])=[O:15])[cH:7][cH:8]1)[N:25]1[CH2:24][CH2:23][N:22]([CH2:20][CH3:21])[CH2:27][CH2:26]1Participants
3
Sources & evidence
- ORD record
- ord-54f5eeea2b0b48d0beba514c5f6980a8
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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