Chloroform → 4-{2-Amino-3-oxo-3-[2-(4-phenyl-1H-imidazol-2-yl)-piperidin-1-yl]-propyl}-N-methyl-benzamide
Reaction equation
[CH2:50]1[CH2:51][CH2:52][NH:53][CH2:54][CH2:55]1.[CH:56]([Cl:57])([Cl:58])[Cl:59].[cH:1]1[c:2]2[c:14]([cH:15][cH:16][cH:49]1)-[c:9]1[c:8]([cH:13][cH:12][cH:11][cH:10]1)[CH:3]2[CH2:4][O:5][C:6](=[O:7])[NH:17][CH:18]([C:19]([N:20]1[CH:21]([c:26]2[nH:27][cH:28][c:29](-[c:31]3[cH:32][cH:33][cH:34][cH:35][cH:36]3)[n:30]2)[CH2:22][CH2:23][CH2:24][CH2:25]1)=[O:37])[CH2:38][c:39]1[cH:40][cH:41][c:42]([C:45]([NH:46][CH3:47])=[O:48])[cH:43][cH:44]1>>[NH2:17][CH:18]([C:19]([N:20]1[CH:21]([c:26]2[nH:27][cH:28][c:29](-[c:31]3[cH:32][cH:33][cH:34][cH:35][cH:36]3)[n:30]2)[CH2:22][CH2:23][CH2:24][CH2:25]1)=[O:37])[CH2:38][c:39]1[cH:40][cH:41][c:42]([C:45]([NH:46][CH3:47])=[O:48])[cH:43][cH:44]1Participants
4
Sources & evidence
- ORD record
- ord-582a1947e0fa4079937f7fab2fa63e26
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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