Ammonia → 4-[5-[(Cyclopropylamino)carbonyl]-2-methylphenyl]-4,5-dihydro-5-oxo-6-[(phenylmethyl)amino]-2-pyrazinecarboxamide

HRID 939399Notes

Reaction equation

HRID 939399 reaction equation
[C:1](#[N:2])[c:3]1[n:4][c:5]([NH:23][CH2:24][c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:6](=[O:22])[n:7](-[c:9]2[cH:10][c:11]([C:12](=[O:13])[NH:14][CH:15]3[CH2:16][CH2:17]3)[cH:18][cH:19][c:20]2[CH3:21])[cH:8]1.[CH3:35][OH:36].[NH3:31].[OH2:34].[OH:32][OH:33]>>[C:1]([NH2:2])([c:3]1[n:4][c:5]([NH:23][CH2:24][c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:6](=[O:22])[n:7](-[c:9]2[cH:10][c:11]([C:12](=[O:13])[NH:14][CH:15]3[CH2:16][CH2:17]3)[cH:18][cH:19][c:20]2[CH3:21])[cH:8]1)=[O:32]

Participants

6

Reactant 5

HCID 222AmmoniaHCID 784Hydrogen PeroxideHCID 887MethanolHCID 962WaterHCID 666864873-[5-Cyano-2-oxo-3-[(phenylmethyl)amino]-1(2H)-pyrazinyl]-N-cyclopropyl-4-methylbenzamide

Product 1

HCID 666864354-[5-[(Cyclopropylamino)carbonyl]-2-methylphenyl]-4,5-dihydro-5-oxo-6-[(phenylmethyl)amino]-2-pyrazinecarboxamide

Sources & evidence

ORD record
ord-5cc5f26a5f05427e8f4a9991fcb8f210
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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