Trifluoroacetic acid → 4-(5-Chloro-2-(tetrahydro-2H-pyran-4-ylamino)pyridin-3-YL)-6-methyl-1,3,5-triazin-2-amine
Reaction equation
[Cl:1][c:2]1[cH:3][c:4](-[c:15]2[n:16][c:17]([N:22]([CH2:23][c:24]3[cH:25][cH:26][c:27]([O:28][CH3:29])[cH:30][cH:31]3)[CH2:32][c:33]3[cH:34][cH:35][c:36]([O:37][CH3:38])[cH:39][cH:40]3)[n:18][c:19]([CH3:21])[n:20]2)[c:5]([NH:8][CH:9]2[CH2:10][CH2:11][O:12][CH2:13][CH2:14]2)[n:6][cH:7]1.[F:41][C:42]([F:43])([F:44])[C:45]([OH:46])=[O:47]>>[Cl:1][c:2]1[cH:3][c:4](-[c:15]2[n:16][c:17]([NH2:22])[n:18][c:19]([CH3:21])[n:20]2)[c:5]([NH:8][CH:9]2[CH2:10][CH2:11][O:12][CH2:13][CH2:14]2)[n:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-493be388f4054abe80d276e4d67f1fba
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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