Bicarbonate Ion → (4-(2-Pyridyloxy)phenyl)methyl chloride

HRID 939565Notes

Reaction equation

HRID 939565 reaction equation
[C:26](=[O:27])([OH:28])[O-:29].[CH2:31]([Cl:32])[Cl:33].[CH3:34][CH2:35][O:36][C:37](=[O:38])[CH3:39].[Na+:30].[S:1]([Cl:2])([Cl:3])=[O:4].[cH:5]1[cH:6][cH:7][n:8][cH:9][cH:10]1.[n:11]1[c:12]([O:17][c:18]2[cH:19][cH:20][c:21]([CH2:24][OH:25])[cH:22][cH:23]2)[cH:13][cH:14][cH:15][cH:16]1>>[Cl:3][CH2:24][c:21]1[cH:20][cH:19][c:18]([O:17][c:12]2[n:11][cH:16][cH:15][cH:14][cH:13]2)[cH:23][cH:22]1

Participants

8

Reactant 7

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 1049PyridineHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 24386Thionyl ChlorideHCID 17859715[4-(Pyrid-2-yloxy)phenyl]methanol

Product 1

HCID 22292927(4-(2-Pyridyloxy)phenyl)methyl chloride

Sources & evidence

ORD record
ord-33b4a388dde64f11ac8a32c2ae88ab5c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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