Tetrahydrofuran → tert-Butyl 5,6-dihydroimidazo(1,2-a)pyrazine-7(8H)-carboxylate

HRID 939623Notes

Reaction equation

HRID 939623 reaction equation
[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[Cl:19][CH2:20][CH2:21][N:22]([C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:30][c:31]1[n:32]([CH2:36][O:37][CH2:38][CH2:39][Si:40]([CH3:41])([CH3:42])[CH3:43])[cH:33][cH:34][n:35]1.[F-:1].[O:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1>>[CH2:21]1[N:22]([C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:30][c:31]2[n:32]([cH:33][cH:34][n:35]2)[CH2:36]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 69559434Carbamic acid, (2-chloroethyl)[[1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-imidazol-2-yl]methyl]-, 1,1-dimethylethyl ester

Product 1

HCID 21955306tert-Butyl 5,6-dihydroimidazo(1,2-a)pyrazine-7(8H)-carboxylate

Sources & evidence

ORD record
ord-a920832733534fafa664a6c8f02e6cde
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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