Tetrahydrofuran → N-[(1-acetyl-4-piperidinyl)methyl]-N'-(4-fluorophenyl)thiourea
Reaction equation
[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][CH:7]([CH2:10][N:11]=[C:12]=[S:13])[CH2:8][CH2:9]1.[F:14][c:15]1[cH:16][cH:17][c:18]([NH2:21])[cH:19][cH:20]1.[O:22]1[CH2:23][CH2:24][CH2:25][CH2:26]1>>[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][CH:7]([CH2:10][NH:11][C:12](=[S:13])[NH:21][c:18]2[cH:17][cH:16][c:15]([F:14])[cH:20][cH:19]2)[CH2:8][CH2:9]1Participants
4
Sources & evidence
- ORD record
- ord-58018b55c6434318aff7239eed4d9ed7
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…