Piperazine → Pyrimido(5,4-d)pyrimidine, 8-(((2,4-dichlorophenyl)methyl)thio)-4-(4-morpholinyl)-2-(1-piperazinyl)-
Reaction equation
[CH2:28]1[CH2:29][NH:30][CH2:31][CH2:32][NH:33]1.[Cl:1][c:2]1[n:3][c:4]([N:22]2[CH2:23][CH2:24][O:25][CH2:26][CH2:27]2)[c:5]2[c:6]([n:7]1)[c:8]([S:12][CH2:13][c:14]1[c:15]([Cl:21])[cH:16][c:17]([Cl:20])[cH:18][cH:19]1)[n:9][cH:10][n:11]2>>[c:2]1([N:30]2[CH2:29][CH2:28][NH:33][CH2:32][CH2:31]2)[n:3][c:4]([N:22]2[CH2:23][CH2:24][O:25][CH2:26][CH2:27]2)[c:5]2[c:6]([n:7]1)[c:8]([S:12][CH2:13][c:14]1[c:15]([Cl:21])[cH:16][c:17]([Cl:20])[cH:18][cH:19]1)[n:9][cH:10][n:11]2Participants
3
Sources & evidence
- ORD record
- ord-c847e1a1cc7f43649ed72ddcf6e2f273
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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