Dichloromethane → Trifluoroacetic acid

HRID 939887Notes

Reaction equation

HRID 939887 reaction equation
[C:1]([N:5]([C:2](=[O:3])[O-:4])[c:9]1[c:10]2[c:14]([c:15]([CH:18]3[CH2:19][CH:20]([OH:24])[CH:21]([OH:23])[CH2:22]3)[cH:16][cH:17]1)[CH2:13][N:12]([CH3:25])[C:11]2=[O:26])([CH3:6])([CH3:7])[CH3:8].[Cl:34][CH2:35][Cl:36].[F:27][C:28]([C:29](=[O:30])[OH:31])([F:32])[F:33]>>[F:27][C:28]([C:29](=[O:30])[OH:31])([F:32])[F:33].[NH2:5][c:9]1[c:10]2[c:14]([c:15]([CH:18]3[CH2:19][CH:20]([OH:24])[CH:21]([OH:23])[CH2:22]3)[cH:16][cH:17]1)[CH2:13][N:12]([CH3:25])[C:11]2=[O:26]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 178479902HCID 178479902, compound

Product 2

HCID 6422Trifluoroacetic acidHCID 672550857-amino-4-(3,4-dihydroxycyclopentyl)-2-methyl-3H-isoindol-1-one

Sources & evidence

ORD record
ord-6acd38241d4141a484b5d6e5c2cf77ef
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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