Imidazole → 4'-{[Tert-butyl(dimethyl)silyl]oxy}-2',6'-dimethylbiphenyl-3-carbaldehyde

HRID 939916Notes

Reaction equation

HRID 939916 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([CH3:6])([CH3:7])[Cl:8].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35].[OH:9][c:10]1[cH:11][c:12]([CH3:25])[c:13](-[c:17]2[cH:18][c:19]([CH:23]=[O:24])[cH:20][cH:21][cH:22]2)[c:14]([CH3:16])[cH:15]1.[nH:26]1[cH:27][cH:28][n:29][cH:30]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([CH3:6])([CH3:7])[O:9][c:10]1[cH:11][c:12]([CH3:25])[c:13](-[c:17]2[cH:18][c:19]([CH:23]=[O:24])[cH:20][cH:21][cH:22]2)[c:14]([CH3:16])[cH:15]1

Participants

5

Reactant 4

HCID 795ImidazoleHCID 6228DimethylformamideHCID 28928tert-Butyldimethylsilyl chlorideHCID 231116914'-Hydroxy-2',6'-dimethyl-[1,1'-biphenyl]-3-carbaldehyde

Product 1

HCID 598383304'-{[Tert-butyl(dimethyl)silyl]oxy}-2',6'-dimethylbiphenyl-3-carbaldehyde

Sources & evidence

ORD record
ord-77fe6aad4dd14ea28ed6380a0166857f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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