Chloride → N-isobutyl-3-bromopyrrolidine-2-one

HRID 939941Notes

Reaction equation

HRID 939941 reaction equation
[Br:9][CH:10]([C:11](=[O:12])[OH:16])[CH2:14][CH2:15][Cl:13].[CH2:22]([N+:23]([CH2:24][CH2:25][CH2:26][CH3:27])([CH2:28][CH2:29][CH2:30][CH3:31])[CH2:32][CH2:33][CH2:34][CH3:35])[CH2:36][CH2:37][CH3:38].[CH2:3]([CH:4]([CH3:5])[CH3:6])[NH2:7].[Cl-:8].[Cl:39][CH2:40][Cl:41].[Na+:2].[OH-:1].[OH2:42].[S:17]([O-:18])([OH:19])(=[O:20])=[O:21]>>[CH2:3]([CH:4]([CH3:5])[CH3:6])[N:7]1[C:11](=[O:12])[CH:10]([Br:9])[CH2:14][CH2:15]1

Participants

10

Reactant 9

HCID 312ChlorideHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6344DichloromethaneHCID 6558IsobutylamineHCID 16028TetrabutylammoniumHCID 61778Sulfate, hydrogenHCID 15486715a-Bromo-g-chlorobutyric acid

Product 1

HCID 23303156N-isobutyl-3-bromopyrrolidine-2-one

Sources & evidence

ORD record
ord-f7db0d0f069b48589ab88e7a0b000fdf
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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