Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 939975Generated: October 26, 2026

Dimethylformamide → (RS)-1-[2-(4,5-Difluoro-1H-benzoimidazol-2-ylmethyl)-piperidin-1-yl]-1-[5-(4-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanone

https://huagongshe.com/reaction/939975

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantHexafluorophosphateHCID 9886—
ReactantDiisopropylethylamineHCID 81531—
Reactant(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 4641409—
Reactant(RS)-4,5-Difluoro-2-piperidin-2-ylmethyl-1H-benzoimidazoleHCID 17973676—
Reactant5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acidHCID 22324125—
Product(RS)-1-[2-(4,5-Difluoro-1H-benzoimidazol-2-ylmethyl)-piperidin-1-yl]-1-[5-(4-fluoro-phenyl)-2-methyl-thiazol-4-yl]-methanoneHCID 17973673—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-3c1a77aa381f4866bbd0d1995b2c1ae7
Source noteValidation data from https://doi.org/10.1039/C8SC04228D