Dichloromethane → HCID 42610297, compound

HRID 940298Notes

Reaction equation

[C:8](#[N:9])[c:10]1[n:11][cH:12][c:13]([NH:16][c:17]2[n:18][cH:19][c:20]([C:38]([NH:39][c:40]3[cH:41][cH:42][cH:43][cH:44][cH:45]3)=[O:46])[c:21]([NH:23][CH2:24][CH:25]3[CH2:26][CH2:27][N:28]([C:31]([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[CH2:29][CH2:30]3)[cH:22]2)[n:14][cH:15]1.[Cl:47][CH2:48][Cl:49].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[C:8](#[N:9])[c:10]1[n:11][cH:12][c:13]([NH:16][c:17]2[n:18][cH:19][c:20]([C:38]([NH:39][c:40]3[cH:41][cH:42][cH:43][cH:44][cH:45]3)=[O:46])[c:21]([NH:23][CH2:24][CH:25]3[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]3)[cH:22]2)[n:14][cH:15]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 59613455Tert-butyl 4-((2-(5-cyanopyrazin-2-ylamino)-5-(phenylcarbamoyl)pyridin-4-ylamino)methyl)piperidine-1-carboxylate

Product 1

HCID 42610297HCID 42610297, compound

Sources & evidence

ORD record: ord-2a3c348140ff4193848fb8f322184248
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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