Trifluoroacetic acid → 2-(3-Bromo-4-methoxyphenyl)-2-methylpropionitrile
Reaction equation
[Br:14][N:15]1[C:16](=[O:17])[CH2:18][CH2:19][C:20]1=[O:21].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([C:9]([C:10]#[N:11])([CH3:12])[CH3:13])[cH:7][cH:8]1.[F:22][C:23]([F:24])([F:25])[C:26]([OH:27])=[O:28]>>[CH3:1][O:2][c:3]1[c:4]([Br:14])[cH:5][c:6]([C:9]([C:10]#[N:11])([CH3:12])[CH3:13])[cH:7][cH:8]1Participants
4
Sources & evidence
- ORD record
- ord-8596b110effe4a7582e10c1e5c8ec53c
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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