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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 940416Generated: October 30, 2026

Hydrogen Bromide → N-[1-(5-chloro-2-pyridinyl)-1-[3-fluoro-5-(trifluoromethyl)phenyl]-2-phenylethyl]-3,3-difluoropyrrolidine-1-carboxamide

https://huagongshe.com/reaction/940416

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen BromideHCID 260—
Reactant3,3-DifluoropyrrolidineHCID 2782827—
Reactant(4-nitrophenyl) N-[1-(5-chloro-2-pyridinyl)-1-[3-fluoro-5-(trifluoromethyl)phenyl]-2-phenylethyl]carbamateHCID 66934387—
ProductN-[1-(5-chloro-2-pyridinyl)-1-[3-fluoro-5-(trifluoromethyl)phenyl]-2-phenylethyl]-3,3-difluoropyrrolidine-1-carboxamideHCID 72463281—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-142be41a74e64b6aabb8fa12989d3551
Source noteValidation data from https://doi.org/10.1039/C8SC04228D