Acetic Acid → 3-Chloro-4-(2,4-difluorobenzyloxy)-1-(3-fluorobenzyl)-1H-pyridin-2-one

HRID 940419Notes

Reaction equation

HRID 940419 reaction equation
[C:34]([OH:35])(=[O:36])[CH3:37].[Cl:26][N:27]1[C:28](=[O:29])[CH2:30][CH2:31][C:32]1=[O:33].[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[cH:7][c:8](=[O:20])[n:9]([CH2:12][c:13]3[cH:14][c:15]([F:19])[cH:16][cH:17][cH:18]3)[cH:10][cH:11]2)[cH:21][cH:22][c:23]([F:25])[cH:24]1>>[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[c:7]([Cl:26])[c:8](=[O:20])[n:9]([CH2:12][c:13]3[cH:14][c:15]([F:19])[cH:16][cH:17][cH:18]3)[cH:10][cH:11]2)[cH:21][cH:22][c:23]([F:25])[cH:24]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 31398ChlorosuccinimideHCID 22050302HCID 22050302, compound

Product 1

HCID 114744543-Chloro-4-(2,4-difluorobenzyloxy)-1-(3-fluorobenzyl)-1H-pyridin-2-one

Sources & evidence

ORD record
ord-12f3d617fe7549449af9a2261b88b557
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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