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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 940509Generated: October 31, 2026

Chloride → Methyl 2-(2-chloro-4-fluorophenyl)-4-(3-ethoxy-3-oxopropanoyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/940509

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantMagnesium CationHCID 888—
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantMethylHCID 3034819—
ReactantPropanedioic acid, monoethyl esterHCID 3595298—
ReactantHCID 66731707HCID 66731707—
ProductMethyl 2-(2-chloro-4-fluorophenyl)-4-(3-ethoxy-3-oxopropanoyl)piperidine-1-carboxylateHCID 66731881—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-909ab3f5b7cf46e1b84bb9d50eef37c6
Source noteValidation data from https://doi.org/10.1039/C8SC04228D