Bromide ion → 4-Chloro-2-(4-ethoxy-4-oxo-butyl)-6-morpholinopyrimidine
Reaction equation
[Br-:1].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH2:2]([CH3:3])[O:4][C:5]([CH2:6][CH2:7][CH2:8][Zn+:9])=[O:10].[Cl:11][c:12]1[n:13][c:14]([N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[cH:15][c:16]([Cl:18])[n:17]1>>[CH2:2]([CH3:3])[O:4][C:5]([CH2:6][CH2:7][CH2:8][c:12]1[n:13][c:14]([N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[cH:15][c:16]([Cl:18])[n:17]1)=[O:10]Participants
5
Sources & evidence
- ORD record
- ord-5edcade5ba8248f6a5c5e59e0e27427b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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