Hydrochloric Acid → (2-Isopropoxy-5-methanesulfonyl-phenyl)-[4-(4-methyl-5-trifluoromethyl-thiazol-2-yl)-piperazin-1-yl]-methanone

HRID 940720Notes

Reaction equation

HRID 940720 reaction equation
[CH3:19][c:20]1[n:21][c:22]([N:29]2[CH2:30][CH2:31][NH:32][CH2:33][CH2:34]2)[s:23][c:24]1[C:25]([F:26])([F:27])[F:28].[CH:1]([CH3:2])([CH3:3])[O:4][c:5]1[c:6]([C:7](=[O:8])[OH:9])[cH:10][c:11]([S:14](=[O:15])(=[O:16])[CH3:17])[cH:12][cH:13]1.[ClH:18]>>[CH:1]([CH3:2])([CH3:3])[O:4][c:5]1[c:6]([C:7](=[O:9])[N:32]2[CH2:31][CH2:30][N:29]([c:22]3[n:21][c:20]([CH3:19])[c:24]([C:25]([F:26])([F:27])[F:28])[s:23]3)[CH2:34][CH2:33]2)[cH:10][c:11]([S:14](=[O:15])(=[O:16])[CH3:17])[cH:12][cH:13]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 211001784-Methyl-2-piperazin-1-yl-5-(trifluoromethyl)-1,3-thiazoleHCID 211002372-Isopropoxy-5-methylsulfonylbenzoic acid

Product 1

HCID 11526054(2-Isopropoxy-5-methanesulfonyl-phenyl)-[4-(4-methyl-5-trifluoromethyl-thiazol-2-yl)-piperazin-1-yl]-methanone

Sources & evidence

ORD record
ord-4cb5c66d2413432a95f9f9cbe0ff9e02
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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