Phosphorus oxychloride → 8-(2-Methoxy-4-cyano-phenyl)-1H,3H-purin-2,6-dione

HRID 940862Notes

Reaction equation

HRID 940862 reaction equation
[CH3:1][O:2][c:3]1[c:4](-[c:12]2[n:13][c:14]3[nH:15][c:16](=[O:22])[nH:17][c:18](=[O:21])[c:19]3[nH:20]2)[cH:5][cH:6][c:7]([C:9](=[O:10])[NH2:11])[cH:8]1.[P:23]([Cl:24])([Cl:25])([Cl:26])=[O:27]>>[CH3:1][O:2][c:3]1[c:4](-[c:12]2[n:13][c:14]3[nH:15][c:16](=[O:22])[nH:17][c:18](=[O:21])[c:19]3[nH:20]2)[cH:5][cH:6][c:7]([C:9]#[N:11])[cH:8]1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 201532438-(2-Methoxy-4-aminocarbonyl-phenyl)-1H,3H-purin-2,6-dione

Product 1

HCID 201532568-(2-Methoxy-4-cyano-phenyl)-1H,3H-purin-2,6-dione

Sources & evidence

ORD record
ord-a17032cedd6d43c39f5660c3c26fe188
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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