Dichloromethane → N-[5-Chloro-4-(tetrahydro-pyran-2-yloxymethyl)-pyridin-3-ylmethyl]-isobutyramide
Reaction equation
[C:21]([CH:22]([CH3:23])[CH3:24])(=[O:25])[Cl:26].[Cl:18][CH2:19][Cl:20].[Cl:1][c:2]1[c:3]([CH2:10][O:11][CH:12]2[O:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[c:4]([CH2:8][NH2:9])[cH:5][n:6][cH:7]1>>[Cl:1][c:2]1[c:3]([CH2:10][O:11][CH:12]2[O:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[c:4]([CH2:8][NH:9][C:21]([CH:22]([CH3:23])[CH3:24])=[O:25])[cH:5][n:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-e0617c0b7fee4879a06775c675d16a76
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…