Methanol → 1,1-Dimethylethyl N-(4-methyl-4-piperidinyl)carbamate

HRID 941007Notes

Reaction equation

HRID 941007 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]([CH3:14])([NH:15][C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH2:12][CH2:13]1.[CH3:23][OH:24].[CH3:25][CH2:26][O:27][C:28](=[O:29])[CH3:30].[OH-:31].[OH-:32].[Pd+2:33]>>[NH:8]1[CH2:9][CH2:10][C:11]([CH3:14])([NH:15][C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 19694923Carbamic acid, n-[4-methyl-1-(phenylmethyl)-4-piperidinyl]-, 1,1-dimethylethyl ester

Product 1

HCID 196913701,1-Dimethylethyl N-(4-methyl-4-piperidinyl)carbamate

Sources & evidence

ORD record
ord-040da52e74c34d04a6f54daae2432e35
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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