Dichloromethane → N-(4-(2,4-Difluorophenoxy)phenyl)-N-(2,2,2-trifluoroethanesulfonyl)amine

HRID 941197Notes

Reaction equation

HRID 941197 reaction equation
[CH2:35]([Cl:36])[Cl:37].[CH3:26][N:27]([CH3:28])[c:29]1[cH:30][cH:31][n:32][cH:33][cH:34]1.[F:10][c:11]1[c:12]([O:13][c:14]2[cH:15][cH:16][c:17]([NH2:18])[cH:19][cH:20]2)[cH:21][cH:22][c:23]([F:25])[cH:24]1.[F:1][C:2]([CH2:3][S:4](=[O:5])(=[O:6])[Cl:7])([F:8])[F:9]>>[F:1][C:2]([CH2:3][S:4](=[O:5])(=[O:6])[NH:18][c:17]1[cH:16][cH:15][c:14]([O:13][c:12]2[c:11]([F:10])[cH:24][c:23]([F:25])[cH:22][cH:21]2)[cH:20][cH:19]1)([F:8])[F:9]

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 142844-(Dimethylamino)pyridineHCID 742422,2,2-Trifluoroethanesulfonyl chlorideHCID 226635574-(2,4-Difluorophenoxy)aniline

Product 1

HCID 22663792N-(4-(2,4-Difluorophenoxy)phenyl)-N-(2,2,2-trifluoroethanesulfonyl)amine

Sources & evidence

ORD record
ord-5a1fb35d36d3493f93bb506957994775
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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