1-Butanol → 6-chloro-N4-(tetrahydro-2H-pyran-4-yl)pyrimidine-2,4,5-triamine
Reaction equation
[C:18](=[O:19])([OH:20])[O-:21].[CH2:23]([OH:24])[CH2:25][CH2:26][CH3:27].[NH2:11][CH:12]1[CH2:13][CH2:14][O:15][CH2:16][CH2:17]1.[NH2:1][c:2]1[n:3][c:4]([Cl:10])[c:5]([NH2:9])[c:6]([Cl:8])[n:7]1.[Na+:22]>>[NH2:1][c:2]1[n:3][c:4]([Cl:10])[c:5]([NH2:9])[c:6]([NH:11][CH:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[n:7]1Participants
6
Sources & evidence
- ORD record
- ord-fb836176d54c4d53938e7272d296635b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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