Hydrochloric Acid → 1-[(5-Methoxychroman-3-YL)methyl]-4-benzylpiperazine

HRID 941323Notes

Reaction equation

HRID 941323 reaction equation
[CH3:27][O:28][c:29]1[c:30]2[c:35]([cH:36][cH:37][cH:38]1)[O:34][CH2:33][CH:32]([C:39](=[O:40])[N:41]1[CH2:42][CH2:43][N:44]([CH2:47][c:48]3[cH:49][cH:50][cH:51][cH:52][cH:53]3)[CH2:45][CH2:46]1)[CH2:31]2.[ClH:26].[F:1][c:2]1[cH:3][cH:4][c:5]2[c:24]([cH:25]1)[CH2:23][CH:7]([C:8]([N:9]1[CH2:10][CH2:11][N:12]([CH2:13][c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[CH2:20][CH2:21]1)=[O:22])[O:6]2>>[CH3:27][O:28][c:29]1[c:30]2[c:35]([cH:36][cH:37][cH:38]1)[O:34][CH2:33][CH:32]([CH2:39][N:41]1[CH2:42][CH2:43][N:44]([CH2:47][c:48]3[cH:49][cH:50][cH:51][cH:52][cH:53]3)[CH2:45][CH2:46]1)[CH2:31]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 108089051-[(5-Methoxychroman-3-yl)carbonyl]-4-benzylpiperazineHCID 214722611-[(5-Fluoro-2,3-dihydrobenzofur-2-yl)carbonyl]-4-benzylpiperazine

Product 1

HCID 106180041-[(5-Methoxychroman-3-YL)methyl]-4-benzylpiperazine

Sources & evidence

ORD record
ord-515b79515cef4e49ac3e33f2e457055e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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