Dichloromethane → 3-Methyl-1-phenyl-1,3,7-triaza-spiro[4.5]decan-4-one

HRID 941504Notes

Reaction equation

HRID 941504 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][C:10]2([C:11](=[O:22])[N:12]([CH3:21])[CH2:13][N:14]2[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:23][CH2:24][CH2:25]1)([CH3:5])([CH3:6])[CH3:7].[Cl:33][CH2:34][Cl:35].[F:26][C:27]([F:28])([F:29])[C:30]([OH:31])=[O:32]>>[NH:8]1[CH2:9][C:10]2([C:11](=[O:22])[N:12]([CH3:21])[CH2:13][N:14]2[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:23][CH2:24][CH2:25]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 710601793-Methyl-4-oxo-1-phenyl-1,3,7-triaza-spiro[4.5]decane-7-carboxylic acid tert-butyl ester

Product 1

HCID 710602063-Methyl-1-phenyl-1,3,7-triaza-spiro[4.5]decan-4-one

Sources & evidence

ORD record
ord-f0377c4572fe4c9593c912b832c0b2bc
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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