Tetrahydrofuran → 3-Bromo-4-ethynylbiphenyl

HRID 941756Notes

Reaction equation

HRID 941756 reaction equation
[Br:19][c:20]1[cH:21][c:22](-[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:23][cH:24][c:25]1[C:26]#[C:27][Si:28]([C:29]([CH3:30])([CH3:31])[CH3:32])([CH3:33])[CH3:34].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[F-:1]>>[Br:19][c:20]1[cH:21][c:22](-[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:23][cH:24][c:25]1[C:26]#[CH:27]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 68817863(3-Bromobiphenyl-4-ylethynyl)-tert-butyldimethylsilane

Product 1

HCID 860607363-Bromo-4-ethynylbiphenyl

Sources & evidence

ORD record
ord-ef86c929be674fa7a299919948f55070
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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