HRID941873

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11776

Triphenylphosphine

C18H15P

2 次

HCID24290

未命名化合物

HCID31275

1,4-Dioxane

C4H8O2

结构：CCC[CH2][Sn]([CH2]CCC)([CH2]CCC)[c]1ccnn1C

HCID21867455

1-Methyl-5-(tributylstannyl)-1H-pyrazole

C16H32N2Sn

HCID59164501

未命名化合物

PRODUCTS

生成物

HCID59164489

2-amino-4-(1-fluoro-ethyl)-5-(2-methyl-2H-pyrazol-3-yl)-benzoic acid methyl ester

C14H16FN3O2

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-82be71ab47f34b2fa3d64e5c0d711c12
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH3:16][n:17]1[n:18][cH:19][cH:20][c:21]1[Sn:22]([CH2:23][CH2:24][CH2:25][CH3:26])([CH2:27][CH2:28][CH2:29][CH3:30])[CH2:31][CH2:32][CH2:33][CH3:34].[CH3:1][O:2][C:3]([c:4]1[c:5]([NH2:14])[cH:6][c:7]([CH:11]([CH3:12])[F:13])[c:8]([I:10])[cH:9]1)=[O:15].[O:35]1[CH2:36][CH2:37][O:38][CH2:39][CH2:40]1.[Pd:41]([Cl:42])[Cl:43].[c:44]1([P:45]([c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[c:52]2[cH:53][cH:54][cH:55][cH:56][cH:57]2)[cH:58][cH:59][cH:60][cH:61][cH:62]1.[c:63]1([P:64]([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)[cH:77][cH:78][cH:79][cH:80][cH:81]1>>[CH3:1][O:2][C:3]([c:4]1[c:5]([NH2:14])[cH:6][c:7]([CH:11]([CH3:12])[F:13])[c:8](-[c:21]2[n:17]([CH3:16])[n:18][cH:19][cH:20]2)[cH:9]1)=[O:15]