Dichloromethane → 1-Benzyl-4-(4-chloro-3-trifluoromethyl-phenyl)-1,2,3,6-tetrahydro-pyridine
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]([OH:14])([c:15]2[cH:16][c:17]([C:22]([F:23])([F:24])[F:25])[c:18]([Cl:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1.[Cl:33][CH2:34][Cl:35].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]=[C:11]([c:15]2[cH:16][c:17]([C:22]([F:23])([F:24])[F:25])[c:18]([Cl:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1Participants
4
Sources & evidence
- ORD record
- ord-fff9128046004c2c93df64722f23b9f8
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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