Hydrochloric Acid → 5-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

HRID 942073Notes

Reaction equation

HRID 942073 reaction equation
[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:6][n:7]1)[nH:8][c:9]([C:11](=[O:12])[OH:13])[cH:10]2.[ClH:14].[NH2:15][CH:16]([C:17](=[O:18])[N:19]1[CH2:20][CH2:21][CH:22]([OH:25])[CH2:23][CH2:24]1)[CH2:26][c:27]1[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:6][n:7]1)[nH:8][c:9]([C:11](=[O:13])[NH:15][CH:16]([C:17](=[O:18])[N:19]1[CH2:20][CH2:21][CH:22]([OH:25])[CH2:23][CH2:24]1)[CH2:26][c:27]1[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]1)[cH:10]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 217108672-Amino-3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)propan-1-oneHCID 446307045-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid

Product 1

HCID 730657965-chloro-N-[3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

Sources & evidence

ORD record
ord-1dc7c0ecec9b4de9a5baa3bf2f3ddd8c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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