p-Toluidine → para-methyl 4-Anilino-1-Boc-piperidine

HRID 942313Notes

Reaction equation

HRID 942313 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[CH3:15][c:16]1[cH:17][cH:18][c:19]([NH2:20])[cH:21][cH:22]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([NH:20][c:19]2[cH:18][cH:17][c:16]([CH3:15])[cH:22][cH:21]2)[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 7813p-ToluidineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 22557837para-methyl 4-Anilino-1-Boc-piperidine

Sources & evidence

ORD record
ord-58b12b5695a14ed4a63bd2fe9d3d6dcc
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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