Benzene → 2-Amino-6-chloro-N-o-tolylbenzamide

HRID 942382Notes

Reaction equation

HRID 942382 reaction equation
[Cl:24][CH:25]([Cl:26])[Cl:27].[NH2:16][c:17]1[c:18]([CH3:23])[cH:19][cH:20][cH:21][cH:22]1.[NH2:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[c:7]([Cl:11])[cH:8][cH:9][cH:10]1.[S:12]([Cl:13])([Cl:14])=[O:15].[cH:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[NH2:1][c:2]1[c:3]([C:4](=[O:6])[NH:16][c:17]2[c:18]([CH3:23])[cH:19][cH:20][cH:21][cH:22]2)[c:7]([Cl:11])[cH:8][cH:9][cH:10]1

Participants

6

Reactant 5

HCID 241BenzeneHCID 6212ChloroformHCID 7242O-ToluidineHCID 24386Thionyl ChlorideHCID 750712-Amino-6-chlorobenzoic acid

Product 1

HCID 124873672-Amino-6-chloro-N-o-tolylbenzamide

Sources & evidence

ORD record
ord-adaad13b7b214f7494260d0fe93c9454
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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