Sodium ion → benzyl 4-(4-hydroxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate

HRID 942389Notes

Reaction equation

HRID 942389 reaction equation
[Cl:48][CH2:49][Cl:50].[F:7][C:8]([F:9])([F:10])[S:11]([O:12][C:13]1=[CH:14][CH2:15][N:16]([C:19](=[O:20])[O:21][CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:17][CH2:18]1)(=[O:29])=[O:30].[Na+:1].[Na+:2].[O-:3][C:4](=[O:5])[O-:6].[O:41]1[CH2:42][CH2:43][O:44][CH2:45][CH2:46]1.[OH2:47].[OH:31][c:32]1[cH:33][cH:34][c:35]([B:38]([OH:39])[OH:40])[cH:36][cH:37]1>>[C:13]1([c:35]2[cH:34][cH:33][c:32]([OH:31])[cH:37][cH:36]2)=[CH:14][CH2:15][N:16]([C:19](=[O:20])[O:21][CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:17][CH2:18]1

Participants

8

Reactant 7

HCID 923Sodium ion2×HCID 962WaterHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 27343604-Hydroxyphenylboronic acidHCID 11303044benzyl 4-(trifluoromethylsulfonyloxy)-5,6-dihydropyridine-1(2H)-carboxylate

Product 1

HCID 66788302benzyl 4-(4-hydroxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate

Sources & evidence

ORD record
ord-fa785ea7fe134f77a0c3664c9614f87b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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