Water → 4-{2-(2,4-dichlorophenyl)-5-methyl-4-[(piperidin-1-ylamino)carbonyl]-1H-imidazol-1-yl}phenyl 3-methylbutane-1-sulfonate

HRID 942470Notes

Reaction equation

HRID 942470 reaction equation
[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[CH3:38][CH:39]([CH2:40][CH2:41][S:42](=[O:43])(=[O:44])[Cl:45])[CH3:46].[Cl:1][c:2]1[c:3](-[c:9]2[n:10](-[c:24]3[cH:25][cH:26][c:27]([OH:30])[cH:28][cH:29]3)[c:11]([CH3:23])[c:12]([C:14](=[O:15])[NH:16][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]3)[n:13]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1.[Cl:48][CH2:49][Cl:50].[OH2:47]>>[Cl:1][c:2]1[c:3](-[c:9]2[n:10](-[c:24]3[cH:25][cH:26][c:27]([O:30][S:42]([CH2:41][CH2:40][CH:39]([CH3:38])[CH3:46])(=[O:43])=[O:44])[cH:28][cH:29]3)[c:11]([CH3:23])[c:12]([C:14](=[O:15])[NH:16][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]3)[n:13]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

6

Reactant 5

HCID 962WaterHCID 6344DichloromethaneHCID 8471TriethylamineHCID 129333273-Methylbutane-1-sulfonyl chlorideHCID 589650752-(2,4-Dichlorophenyl)-1-(4-hydroxyphenyl)-5-methyl-1H-imidazole-4-carboxylic acid piperidin-1-ylamide

Product 1

HCID 116998384-{2-(2,4-dichlorophenyl)-5-methyl-4-[(piperidin-1-ylamino)carbonyl]-1H-imidazol-1-yl}phenyl 3-methylbutane-1-sulfonate

Sources & evidence

ORD record
ord-81a349f6bfea4e0393b3decce834db19
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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