Ethanol → tert-Butyl 2-Hydroxy-2-(4-(hydroxymethyl)phenyl)ethyl(methyl)carbamate

HRID 942474Notes

Reaction equation

HRID 942474 reaction equation
[BH4-:24].[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:21][CH2:22][OH:23].[CH:1](=[O:2])[c:3]1[cH:4][cH:5][c:6]([CH:9]([CH2:10][N:11]([C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[CH3:19])[OH:20])[cH:7][cH:8]1.[Na+:25]>>[CH2:1]([OH:2])[c:3]1[cH:4][cH:5][c:6]([CH:9]([CH2:10][N:11]([C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[CH3:19])[OH:20])[cH:7][cH:8]1

Participants

6

Reactant 5

HCID 702EthanolHCID 923Sodium ionHCID 8028TetrahydrofuranHCID 28123BorohydrideHCID 22574298tert-Butyl 2-(4-Formylphenyl)-2-hydroxyethyl(methyl)carbamate

Product 1

HCID 22574345tert-Butyl 2-Hydroxy-2-(4-(hydroxymethyl)phenyl)ethyl(methyl)carbamate

Sources & evidence

ORD record
ord-d50cb38ced5e413b88e5d82e0cc2a677
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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