Bromide ion → tert-Butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate

HRID 942511Notes

Reaction equation

HRID 942511 reaction equation
[Br-:16].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH:14]=[O:15])[CH2:12][CH2:13]1.[CH3:17][Mg+:18].[O:19]1[CH2:20][CH2:21][CH2:22][CH2:23]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH:14]([OH:15])[CH3:17])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 1514430tert-Butyl 4-formylpiperidine-1-carboxylateHCID 178477777HCID 178477777, compound

Product 1

HCID 21989903tert-Butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-90f7fbabbc6a476986820700f303ed20
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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