Dichloromethane → N-(5-formyl-2-methylphenyl)-4-[(4-phenylquinazolin-2-yl)amino]benzamide

HRID 942603Notes

Reaction equation

HRID 942603 reaction equation
[CH2:41]([Al+:42][CH2:43][CH:44]([CH3:45])[CH3:46])[CH:47]([CH3:48])[CH3:49].[CH3:1][N:2]([C:3]([c:4]1[cH:5][c:6]([NH:11][C:12](=[O:13])[c:14]2[cH:15][cH:16][c:17]([NH:20][c:21]3[n:22][c:23]4[cH:24][cH:25][cH:26][cH:27][c:28]4[c:29](-[c:31]4[cH:32][cH:33][cH:34][cH:35][cH:36]4)[n:30]3)[cH:18][cH:19]2)[c:7]([CH3:10])[cH:8][cH:9]1)=[O:37])[O:38][CH3:39].[CH3:50][CH2:51][O:52][C:53](=[O:54])[CH3:55].[Cl:56][CH2:57][Cl:58].[H-:40]>>[CH:3]([c:4]1[cH:5][c:6]([NH:11][C:12](=[O:13])[c:14]2[cH:15][cH:16][c:17]([NH:20][c:21]3[n:22][c:23]4[cH:24][cH:25][cH:26][cH:27][c:28]4[c:29](-[c:31]4[cH:32][cH:33][cH:34][cH:35][cH:36]4)[n:30]3)[cH:18][cH:19]2)[c:7]([CH3:10])[cH:8][cH:9]1)=[O:37]

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 166653HydrideHCID 16686348Bis(2-methylpropyl)alumanyliumHCID 25070163N,4-dimethyl-N-(methyloxy)-3-[({4-[(4-phenylquinazolin-2-yl)amino]phenyl}carbonyl)amino]benzamide

Product 1

HCID 57662899N-(5-formyl-2-methylphenyl)-4-[(4-phenylquinazolin-2-yl)amino]benzamide

Sources & evidence

ORD record
ord-6e7060dabbb04305a65ebda3eb0bcb94
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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