N-methyl-2-pyrrolidone → 3-Bromo-5-methylbenzonitrile

HRID 942711Notes

Reaction equation

HRID 942711 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH3:9])[cH:5][c:6]([Br:8])[cH:7]1.[CH3:13][N:14]1[CH2:15][CH2:16][CH2:17][C:18]1=[O:19].[Cu:10][C:11]#[N:12]>>[Br:1][c:2]1[cH:3][c:4]([CH3:9])[cH:5][c:6]([C:11]#[N:12])[cH:7]1

Participants

4

Reactant 3

HCID 13387N-methyl-2-pyrrolidoneHCID 153613,5-DibromotolueneHCID 178418546HCID 178418546, compound

Product 1

HCID 145678583-Bromo-5-methylbenzonitrile

Sources & evidence

ORD record
ord-b9b0c8963eda497f9890a089aba642ac
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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