Diethyl Ether → 2-isopropyl-4-methoxy-N,N-diethylbenzamide

HRID 943047Notes

Reaction equation

HRID 943047 reaction equation
[CH2:13]([Li:14])[CH2:15][CH2:16][CH3:17].[CH2:18]([CH3:19])[N:20]([C:21](=[O:22])[Cl:23])[CH2:24][CH3:25].[CH3:26][CH2:27][O:28][CH2:29][CH3:30].[CH:1]([CH3:2])([CH3:3])[c:4]1[c:5]([Br:12])[cH:6][cH:7][c:8]([O:10][CH3:11])[cH:9]1>>[CH:1]([CH3:2])([CH3:3])[c:4]1[c:5]([C:21]([N:20]([CH2:18][CH3:19])[CH2:24][CH3:25])=[O:22])[cH:6][cH:7][c:8]([O:10][CH3:11])[cH:9]1

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 6916Diethylcarbamoyl chlorideHCID 117464064-Bromo-3-isopropylanisoleHCID 178418339Butyllithium

Product 1

HCID 102643402-isopropyl-4-methoxy-N,N-diethylbenzamide

Sources & evidence

ORD record
ord-1432161c55f348a1b08e214dab284407
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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