Water → 2-Methyl-2-({4-[2-(methyl{5-[4-(trifluoromethoxy)phenyl]pyrimidin-2-yl}amino)ethyl]-1,3-thiazol-2-yl}thio)propionic acid tert-butyl ester

HRID 943094Notes

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([C:7]([CH3:8])([S:9][c:10]1[s:11][cH:12][c:13]([CH2:15][CH2:16][NH:17][c:18]2[n:19][cH:20][c:21](-[c:24]3[cH:25][cH:26][c:27]([O:30][C:31]([F:32])([F:33])[F:34])[cH:28][cH:29]3)[cH:22][n:23]2)[n:14]1)[CH3:35])=[O:36].[CH3:37][I:38].[CH3:40][CH2:41][CH2:42][CH2:43][O-:44].[CH3:45][N:46]([CH3:47])[CH:48]=[O:49].[K:39].[OH2:50]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([C:7]([CH3:8])([S:9][c:10]1[s:11][cH:12][c:13]([CH2:15][CH2:16][N:17]([c:18]2[n:19][cH:20][c:21](-[c:24]3[cH:25][cH:26][c:27]([O:30][C:31]([F:32])([F:33])[F:34])[cH:28][cH:29]3)[cH:22][n:23]2)[CH3:40])[n:14]1)[CH3:35])=[O:36]