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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 943126Generated: November 1, 2026

Tetrahydrofuran → 2-{[4-(5-fluoropyridin-2-yl)phenyl]acetyl}-N,N-dimethyl-4-[2-methyl-2-(trifluoromethyl)but-3-en-1-yl]-1H-imidazole-1-sulfonamide

https://huagongshe.com/reaction/943126

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantN,N-dimethyl-4-[2-methyl-2-(trifluoromethyl)but-3-en-1-yl]-1H-imidazole-1-sulfonamideHCID 59140382—
ReactantMethyl [4-(5-fluoropyridin-2-yl)phenyl]acetateHCID 86637794—
ReactantButyllithiumHCID 178418339—
Product2-{[4-(5-fluoropyridin-2-yl)phenyl]acetyl}-N,N-dimethyl-4-[2-methyl-2-(trifluoromethyl)but-3-en-1-yl]-1H-imidazole-1-sulfonamideHCID 66705598—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-7d22b713815144148300ac71f19b1de2
Source noteValidation data from https://doi.org/10.1039/C8SC04228D