Tetrahydrofuran → 2-{[4-(5-fluoropyridin-2-yl)phenyl]acetyl}-N,N-dimethyl-4-[2-methyl-2-(trifluoromethyl)but-3-en-1-yl]-1H-imidazole-1-sulfonamide

HRID 943126Notes

Reaction equation

[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:6][N:7]([S:8](=[O:9])(=[O:10])[n:11]1[cH:12][n:13][c:14]([CH2:16][C:17]([CH:18]=[CH2:19])([C:20]([F:21])([F:22])[F:23])[CH3:24])[cH:15]1)[CH3:25].[F:26][c:27]1[cH:28][cH:29][c:30](-[c:33]2[cH:34][cH:35][c:36]([CH2:39][C:40](=[O:41])[O:42][CH3:43])[cH:37][cH:38]2)[n:31][cH:32]1.[O:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1>>[CH3:6][N:7]([S:8](=[O:9])(=[O:10])[n:11]1[c:12]([C:40]([CH2:39][c:36]2[cH:35][cH:34][c:33](-[c:30]3[cH:29][cH:28][c:27]([F:26])[cH:32][n:31]3)[cH:38][cH:37]2)=[O:41])[n:13][c:14]([CH2:16][C:17]([CH:18]=[CH2:19])([C:20]([F:21])([F:22])[F:23])[CH3:24])[cH:15]1)[CH3:25]