Potassium Cation → [5-Methyl-2-(trifluoromethyl)phenyl]-[3-[(2-phenylpyrimidin-4-yl)amino]pyrrolidin-1-yl]methanone

HRID 943148Notes

Reaction equation

HRID 943148 reaction equation
[CH3:39][N:40]([CH3:41])[C:42](=[O:43])[CH3:44].[Cl:1][c:2]1[n:3][c:4](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[n:5][cH:6][cH:7]1.[K+:33].[K+:34].[NH2:14][CH:15]1[CH2:16][N:17]([C:20](=[O:21])[c:22]2[c:23]([C:29]([F:30])([F:31])[F:32])[cH:24][cH:25][c:26]([CH3:28])[cH:27]2)[CH2:18][CH2:19]1.[O-:35][C:36]([O-:37])=[O:38]>>[c:2]1([NH:14][CH:15]2[CH2:16][N:17]([C:20](=[O:21])[c:22]3[c:23]([C:29]([F:30])([F:31])[F:32])[cH:24][cH:25][c:26]([CH3:28])[cH:27]3)[CH2:18][CH2:19]2)[n:3][c:4](-[c:8]2[cH:9][cH:10][cH:11][cH:12][cH:13]2)[n:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 31374DimethylacetamideHCID 2591574-Chloro-2-phenylpyrimidineHCID 68731648(3-Aminopyrrolidin-1-yl)-[5-methyl-2-(trifluoromethyl)phenyl]methanone

Product 1

HCID 68731530[5-Methyl-2-(trifluoromethyl)phenyl]-[3-[(2-phenylpyrimidin-4-yl)amino]pyrrolidin-1-yl]methanone

Sources & evidence

ORD record
ord-2c894f775ca9415a86e4159f9e4b6cd6
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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