Hydrochloric Acid → 2-[4-[4,5-bis(4-chlorophenyl)-1-[4-(2-methylsulfonylethyl)piperazine-1-carbonyl]-4,5-dihydroimidazol-2-yl]-3-ethoxyphenyl]-N,N-diethyl-2-methylpropanamide

HRID 943168Notes

Reaction equation

HRID 943168 reaction equation
[CH3:44][S:45](=[O:46])(=[O:47])[CH2:48][CH2:49][N:50]1[CH2:51][CH2:52][NH:53][CH2:54][CH2:55]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[N:9]=[C:10]([c:23]3[c:24]([O:39][CH2:40][CH3:41])[cH:25][c:26]([C:29]([CH3:30])([CH3:31])[C:32]([N:33]([CH2:34][CH3:35])[CH2:36][CH3:37])=[O:38])[cH:27][cH:28]3)[N:11]([C:20](=[O:21])[Cl:22])[CH:12]2[c:13]2[cH:14][cH:15][c:16]([Cl:19])[cH:17][cH:18]2)[cH:6][cH:7]1.[ClH:42].[ClH:43]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]2[N:9]=[C:10]([c:23]3[c:24]([O:39][CH2:40][CH3:41])[cH:25][c:26]([C:29]([CH3:30])([CH3:31])[C:32]([N:33]([CH2:34][CH3:35])[CH2:36][CH3:37])=[O:38])[cH:27][cH:28]3)[N:11]([C:20](=[O:21])[N:53]3[CH2:52][CH2:51][N:50]([CH2:49][CH2:48][S:45]([CH3:44])(=[O:46])=[O:47])[CH2:55][CH2:54]3)[CH:12]2[c:13]2[cH:14][cH:15][c:16]([Cl:19])[cH:17][cH:18]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric Acid2×HCID 38019591-(2-(Methylsulfonyl)ethyl)piperazineHCID 873230014,5-Bis(4-chlorophenyl)-2-[4-[1-(diethylamino)-2-methyl-1-oxopropan-2-yl]-2-ethoxyphenyl]-4,5-dihydroimidazole-1-carbonyl chloride

Product 1

HCID 670125552-[4-[4,5-bis(4-chlorophenyl)-1-[4-(2-methylsulfonylethyl)piperazine-1-carbonyl]-4,5-dihydroimidazol-2-yl]-3-ethoxyphenyl]-N,N-diethyl-2-methylpropanamide

Sources & evidence

ORD record
ord-a25fcd8e8326422c83dc827b3e08b56f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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