Tetrahydrofuran → 1-Tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

HRID 943381Notes

Reaction equation

HRID 943381 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[OH:16])[CH2:10][CH:11]([OH:13])[CH2:12]1.[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[N+:17](=[N-:18])=[CH2:19]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[O:16][CH3:19])[CH2:10][CH:11]([OH:13])[CH2:12]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 9550DiazomethaneHCID 3352551-((Tert-butoxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid

Product 1

HCID 51482991-Tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

Sources & evidence

ORD record
ord-abddf2449b624ceb9e2ca99dd23154d2
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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