Diisobutylaluminum hydride → 3-[4-[3,5-Bis(trifluoromethyl)phenyl]phenyl]but-2-en-1-ol
Reaction equation
[CH3:1][CH:2]([CH2:3][AlH:4][CH2:5][CH:6]([CH3:7])[CH3:8])[CH3:9].[F:10][C:11]([c:12]1[cH:13][c:14](-[c:22]2[cH:23][cH:24][c:25]([C:28](=[CH:29][C:30](=[O:31])[O:32][CH2:33][CH3:34])[CH3:35])[cH:26][cH:27]2)[cH:15][c:16]([C:18]([F:19])([F:20])[F:21])[cH:17]1)([F:36])[F:37]>>[F:10][C:11]([c:12]1[cH:13][c:14](-[c:22]2[cH:23][cH:24][c:25]([C:28](=[CH:29][CH2:30][OH:31])[CH3:35])[cH:26][cH:27]2)[cH:15][c:16]([C:18]([F:19])([F:20])[F:21])[cH:17]1)([F:36])[F:37]Participants
3
Sources & evidence
- ORD record
- ord-4d91879bbf73420bb6770d2b8d4289da
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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